The ultimate weight loss drink that can even deliver drugs and help premature babies: Researchers reveal MILK could be engineered to give it added properties


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Researchers have uncovered exactly how we digest milk - and say it could be used as a superdrink.

The breakthrough lead to the development of new formulas for premature babies, weight loss drinks and potentially new drug delivery systems.

The research is the first time it has been known exactly how milk is digested.

Milk could be given added properties allowing it to do everything from deliver drugs to make us feel full and act as a diet drink.

Milk could be given added properties allowing it to do everything from deliver drugs to make us feel full and act as a diet drink.

HOW THEY DID IT

The researchers accessed specialist instruments at the Australian Synchrotron to simulate digestion and accelerate the research.

Using enzymes present in the body, water was added to milk fat to break it down, and the Synchrotron's small angle X-ray scattering beam showed that when digested, the by-products of milk become highly organised.

The structure is similar to a sponge, potentially enhancing the absorption of milk's healthy fats.

Published in the journal ACS Nano, the Monash University research shows how its fats interact with the digestive system until now.

'By unlocking the detailed structure of milk we have the potential to create milk loaded with fat soluble vitamins and brain building molecules for premature babies, or a drink that slows digestion so people feel fuller for longer,'  said Dr Stefan Salentinig, who led the research.

'We could even harness milk's ability as a 'carrier' to develop new forms of drug delivery.'

'By chemically recreating the digestive system in a glass beaker and adding cows' milk, the team found that milk has a unique structure – an emulsion of fats, nutrients and water forms a structure which enhances digestion.

The team looked at the nanostructure of milk to find out how its components interact with the human digestive system.

They discovered milk has a highly geometrically ordered structure when being digested.

 

Dr Salentinig said the research provides a blueprint for the development of new milk products. It could also lead to a new system for drug delivery.

As well as laboratory work at MIPS, the researchers accessed specialist instruments at the Australian Synchrotron to simulate digestion and accelerate the research.

Using enzymes present in the body, water was added to milk fat to break it down, and the Synchrotron's small angle X-ray scattering beam showed that when digested, the by-products of milk become highly organised.

The team looked at the nanostructure of milk to find out how its components interact with the human digestive system. They discovered milk has a highly geometrically ordered structure when being digested.

The team looked at the nanostructure of milk to find out how its components interact with the human digestive system. They discovered milk has a highly geometrically ordered structure when being digested.

Dr Salentinig said the structure is similar to a sponge, potentially enhancing the absorption of milk's healthy fats.

'We knew about the building blocks of milk and that milk fat has significant influence on the flavor, texture and nutritional value of all dairy food.

'But what we didn't know was the structural arrangement of this fat during digestion,' he said.

'We found that when the body starts the digestion process, an enzyme called lipase breaks down the fat molecules to form a highly geometrically ordered structure.

'These small and highly organised components enable fats, vitamins and lipid-soluble drugs to cross cell membranes and get into the circulatory system,' Dr Salentinig said.



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